BDBM467272 (S)-3-(1-acryloylpiperidin-3-yl)-7-amino-1-(4-phenoxyphenyl)-1,5-dihydro-4H-pyrrolo[2,3-d]pyridazin-4-one ::US10800785, Example 11

SMILES Nc1n[nH]c(=O)c2c(cn(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CCCN(C1)C(=O)C=C

InChI Key InChIKey=CAHJEPYULYNIHI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 467272   

TargetTyrosine-protein kinase BTK(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM467272((S)-3-(1-acryloylpiperidin-3-yl)-7-amino-1-(4-phen...)
Affinity DataIC50: 40nMAssay Description:MTS testing kit was purchased from Promega. The DMEM, Fetal bovine serum and Penicillin-Streptomycin were purchased from Gibco. Dimethyl sulfoxide (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent