BDBM468429 US10806785, Example 73::cis-4-((2-((2,2'-dichloro-3'- (1-methyl-5-(tetrahydro-2H- pyran-4-yl)-4,5,6,7- tetrahydro-1H-imidazo [4,5-c]pyridine-2- carboxamido)-[1,1'- biphenyl]-3-yl)carbamoyl)- 1-methyl-1,4,6,7- tetrahydro-5H- imidazo[4,5-c]pyridin-5- yl)methyl)cyclohexane-1- carboxylic acid

SMILES Cn1c(C(=O)Nc2cccc(-c3cccc(NC(=O)c4nc5c(n4C)CCN(C4CCOCC4)C5)c3Cl)c2Cl)nc2c1CCN(C[C@H]1CC[C@@H](C(=O)O)CC1)C2

InChI Key InChIKey=KDCMCARJCJXNJM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 468429   

LigandChemical structure of BindingDB Monomer ID 468429BDBM468429(US10806785, Example 73 | cis-4-((2-((2,2'-dichloro...)
Affinity DataIC50: 0.100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent