BDBM468612 US10807944, Compound SR-4372::US11731934, Compound SR-4372

SMILES CCCCNNC(=O)c1ccc(cc1)-c1cc(C)cc(F)c1

InChI Key InChIKey=RVPBGXMIWLAEPK-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 468612   

TargetHistone deacetylase 3(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468612(US10807944, Compound SR-4372 | US11731934, Compoun...)
Affinity DataIC50: 380nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468612(US10807944, Compound SR-4372 | US11731934, Compoun...)
Affinity DataIC50: 380nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2023
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468612(US10807944, Compound SR-4372 | US11731934, Compoun...)
Affinity DataIC50: 760nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468612(US10807944, Compound SR-4372 | US11731934, Compoun...)
Affinity DataIC50: 760nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2023
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468612(US10807944, Compound SR-4372 | US11731934, Compoun...)
Affinity DataIC50: 1.20E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468612(US10807944, Compound SR-4372 | US11731934, Compoun...)
Affinity DataIC50: 1.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2023
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468612(US10807944, Compound SR-4372 | US11731934, Compoun...)
Affinity DataIC50: 3.60E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468612(US10807944, Compound SR-4372 | US11731934, Compoun...)
Affinity DataIC50: 3.60E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468612(US10807944, Compound SR-4372 | US11731934, Compoun...)
Affinity DataIC50: 3.70E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468612(US10807944, Compound SR-4372 | US11731934, Compoun...)
Affinity DataIC50: 3.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2023
Entry Details
US Patent