BDBM470041 CIS-N-(Carbamoyl-methyl)-2-[1-(cyclobutyl-methyl)-8-dimethylamino-8-(3- fluorophenyl)-2-oxo-1,3-diazaspiro[4.5]decan-3-yl]-N-methyl-acetamide::US10807989, Example SC_1349

SMILES CN(CC(N)=O)C(=O)CN1C[C@]2(CC[C@](c3cccc(F)c3)(N(C)C)CC2)N(CC2CCC2)C1=O

InChI Key InChIKey=OYHQOPIJPIGUSX-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 470041   

TargetNociceptin receptor(Human)
GrÜNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 470041BDBM470041(CIS-N-(Carbamoyl-methyl)-2-[1-(cyclobutyl-methyl)-...)
Affinity DataKi:  1nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl, 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
GrÜNenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 470041BDBM470041(CIS-N-(Carbamoyl-methyl)-2-[1-(cyclobutyl-methyl)-...)
Affinity DataKi:  165nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent