BDBM470064 US10807993, Example 3::US10807993, Example 4

SMILES Cc1nccn1CC(=O)N1CC[C@@]2(CC1)COC1C(C2)C(C)(C)Oc2ccc(Cl)cc12

InChI Key InChIKey=KUSQHMDFDNXTBT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 470064   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM470064(US10807993, Example 4 | US10807993, Example 3)
Affinity DataIC50: 200nMAssay Description:To a cultured CHO cell strain which stably expresses hERG was added each test compound to adjust the final concentration of DMSO to 0.0135 to 0.5%. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM470064(US10807993, Example 4 | US10807993, Example 3)
Affinity DataIC50: 300nMAssay Description:To a cultured CHO cell strain which stably expresses hERG was added each test compound to adjust the final concentration of DMSO to 0.0135 to 0.5%. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent