BDBM470101 US10807993, Example 41::US10807993, Example 42

SMILES CC1(C)Oc2cc(Cl)ccc2C2OC[C@]3(CCN(CCn4ccnc4)CC3)CC12

InChI Key InChIKey=QKAZUVQTHFXMLS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 470101   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM470101(US10807993, Example 42 | US10807993, Example 41)
Affinity DataIC50: 700nMAssay Description:To a cultured CHO cell strain which stably expresses hERG was added each test compound to adjust the final concentration of DMSO to 0.0135 to 0.5%. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM470101(US10807993, Example 42 | US10807993, Example 41)
Affinity DataIC50: 1.40E+3nMAssay Description:To a cultured CHO cell strain which stably expresses hERG was added each test compound to adjust the final concentration of DMSO to 0.0135 to 0.5%. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent