BDBM470125 US10807994, Compound 1.1::US10807994, Compound 1.32::US10807994, Example S-1

SMILES CN1CCN(CC1)c1ccc(Nc2ncc3C(=O)N(COc3n2)c2c(Cl)cccc2Cl)cc1

InChI Key InChIKey=HFAXUCKUBGEMKA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 470125   

TargetWee1-like protein kinase(Human)
Nuvation Bio

US Patent
LigandPNGBDBM470125(US10807994, Compound 1.32 | US10807994, Example S-...)
Affinity DataIC50: 56nMAssay Description:IC50 values of compounds against WEE1 kinase enzyme were determined by LanthaScreen Terbium Labeled TR-FRET assay. Kinase assays were performed in 1×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetWee1-like protein kinase(Human)
Nuvation Bio

US Patent
LigandPNGBDBM470125(US10807994, Compound 1.32 | US10807994, Example S-...)
Affinity DataIC50: 366nMAssay Description:IC50 values of compounds against WEE1 kinase enzyme were determined by LanthaScreen Terbium Labeled TR-FRET assay. Kinase assays were performed in 1×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent