BDBM470127 US10807994, Compound 1.3::US10807994, Example S-3

SMILES CC1(C)CN(Cc2cc(Nc3ncc4C(=O)N(COc4n3)c3c(Cl)cccc3Cl)ccc12)C(=O)CO

InChI Key InChIKey=OFMJUDHJVRGHOG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 470127   

TargetWee1-like protein kinase(Human)
Nuvation Bio

US Patent
LigandPNGBDBM470127(US10807994, Example S-3 | US10807994, Compound 1.3)
Affinity DataIC50: 40nMAssay Description:IC50 values of compounds against WEE1 kinase enzyme were determined by LanthaScreen Terbium Labeled TR-FRET assay. Kinase assays were performed in 1×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent