BDBM470191 US10807994, Compound 1.173::US10807994, Example S-67

SMILES C[C@@H]1CN(CCN1)c1ccc(Nc2ncc3C(=O)N(COc3n2)c2c(Cl)cccc2Cl)cc1

InChI Key InChIKey=MBPCOHCMHHMJMR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 470191   

TargetWee1-like protein kinase(Human)
Nuvation Bio

US Patent
LigandPNGBDBM470191(US10807994, Example S-67 | US10807994, Compound 1....)
Affinity DataIC50: 87nMAssay Description:IC50 values of compounds against WEE1 kinase enzyme were determined by LanthaScreen Terbium Labeled TR-FRET assay. Kinase assays were performed in 1×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent