BDBM470221 US10807994, Compound 1.246::US10807994, Example S-98

SMILES CC1(C)NCCc2cc(Nc3ncc4C(=O)N(CSc4n3)c3c(Cl)cccc3Cl)ccc12

InChI Key InChIKey=WIQJYRHDKBENHW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 470221   

TargetWee1-like protein kinase(Human)
Nuvation Bio

US Patent
LigandPNGBDBM470221(US10807994, Example S-98 | US10807994, Compound 1....)
Affinity DataIC50: 61nMAssay Description:IC50 values of compounds against WEE1 kinase enzyme were determined by LanthaScreen Terbium Labeled TR-FRET assay. Kinase assays were performed in 1×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent