BDBM471660 US10822338, Example 34A::US10822338, Example 34B

SMILES COc1cccc2c3nc(nn3c(N)nc12)[C@@H]1CN(CC(F)F)CC(F)(F)C1

InChI Key InChIKey=PKPHVIYURJVTMV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 471660   

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM471660(US10822338, Example 34A | US10822338, Example 34B)
Affinity DataKi:  1.10nMAssay Description:Binding affinities of compounds of the invention for the human A2A receptor were determined in a competition binding assay using Scintillation Proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM471660(US10822338, Example 34A | US10822338, Example 34B)
Affinity DataKi:  4.70nMAssay Description:Binding affinities of compounds of the invention for the human A2A receptor were determined in a competition binding assay using Scintillation Proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
US Patent