BDBM471668 7-methoxy-2-((3R)-1- ((3-methoxyphenyl) carbonyl)piperidin-3- yl)[1,2,4]triazolo[1,5- c]quinazolin-5-amine::US10822338, Example 41

SMILES COc1cccc(c1)C(=O)N1CCC[C@H](C1)c1nc2c3cccc(OC)c3nc(N)n2n1

InChI Key InChIKey=RYJKBXQRNKPNDW-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 471668   

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM471668(7-methoxy-2-((3R)-1- ((3-methoxyphenyl) carbonyl)p...)
Affinity DataKi:  1.90nMAssay Description:Binding affinities of compounds of the invention for the human A2A receptor were determined in a competition binding assay using Scintillation Proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
US Patent