BDBM472233 2-((1R,2R)-2-cyanocyclopropyl)-1-((2,2-difluorobenzo[d][1,3]dioxol-4-::US10829481, Compound I-57

SMILES CCS(=O)(=O)c1ccc(CNC(=O)c2ccc3n(Cc4cccc5OC(F)(F)Oc45)c(nc3c2)[C@@H]2C[C@H]2C#N)cc1

InChI Key InChIKey=GJLSTTJUPCFLFP-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472233   

TargetNuclear receptor ROR-gamma(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 472233BDBM472233(US10829481, Compound I-57 | 2-((1R,2R)-2-cyanocycl...)
Affinity DataKi: <100nMAssay Description:Compounds described herein were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-ligand (RL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent