BDBM472317 (S)-1-(1-(2,2-difluorobenzo[d][1,3]dioxol-4-yl)ethyl)-2-ethyl-N-(4-::US10829481, Compound I-125.1

SMILES CCc1nc2cc(ccc2n1[C@@H](C)c1cccc2OC(F)(F)Oc12)C(=O)NCc1ccc(cc1)S(=O)(=O)CC

InChI Key InChIKey=WUIHVMURLWRCTJ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472317   

TargetNuclear receptor ROR-gamma(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 472317BDBM472317((S)-1-(1-(2,2-difluorobenzo[d][1,3]dioxol-4-yl)eth...)
Affinity DataKi: <100nMAssay Description:Compounds described herein were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-ligand (RL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent