BDBM472480 (R)-N-(1-Acryloylpiperidin-3-yl)-5-(*S)-(6-isopropoxy-4-::US10822348, Example 789

SMILES C=CC(=O)N1CCC[C@@H](NCc2sc3nccc4c3c2NC(=O)N4c2cnc(OC(C)C)cc2C)C1

InChI Key InChIKey=KKLCKGMDUDEGOT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472480   

TargetTyrosine-protein kinase BTK [386-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 472480BDBM472480((R)-N-(1-Acryloylpiperidin-3-yl)-5-(*S)-(6-isoprop...)
Affinity DataIC50: 7.94nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
US Patent