BDBM472730 5-(2,5-difluorophenyl)-pyrrolidin-3-one ::US10829492, Example 6

SMILES NC(=O)c1c(N)nn2ccc(nc12)N1CCCC1c1cc(F)ccc1F

InChI Key InChIKey=LOHSQDXMJAKLOV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472730   

TargetHigh affinity nerve growth factor receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM472730(5-(2,5-difluorophenyl)-pyrrolidin-3-one | US10829...)
Affinity DataIC50: 1nMAssay Description:TrkA, TrkB and TrkC:A testing platform for TrkA, TrkB and TrkC kinase activity was established based on Homogeneous Time-Resolved Fluorescence (HTRF)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent