BDBM472913 (R)-3-propyl-6,6a,7,8,9,10-hexahydro-5H- pyrazino[1,2-a][1,8]naphthyridine::US10836764, Compound 103

SMILES CCCc1cnc2N3CCNC[C@H]3CCc2c1

InChI Key InChIKey=XTWJJKFHLIDCOK-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 472913   

Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM472913((R)-3-propyl-6,6a,7,8,9,10-hexahydro-5H- pyrazino[...)
Affinity DataKi:  2.5nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM472913((R)-3-propyl-6,6a,7,8,9,10-hexahydro-5H- pyrazino[...)
Affinity DataKi:  22.1nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM472913((R)-3-propyl-6,6a,7,8,9,10-hexahydro-5H- pyrazino[...)
Affinity DataKi:  35.4nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent