BDBM472997 (R)-4-(isopropoxymethyl)-6,6a,7,8,9,10- hexahydro-5H-pyrazino[1,2-a][1,8]naphthyridine::US10836764, Compound 145

SMILES CC(C)OCc1ccnc2N3CCNC[C@H]3CCc12

InChI Key InChIKey=ZFNONDAYGNEJHH-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 472997   

Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM472997((R)-4-(isopropoxymethyl)-6,6a,7,8,9,10- hexahydro-...)
Affinity DataKi:  13.8nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM472997((R)-4-(isopropoxymethyl)-6,6a,7,8,9,10- hexahydro-...)
Affinity DataKi:  209nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM472997((R)-4-(isopropoxymethyl)-6,6a,7,8,9,10- hexahydro-...)
Affinity DataKi:  222nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent