BDBM473 (Hydroxyethyl)urea Isostere deriv. 1::benzyl N-[(1S)-2-carbamoyl-1-{[(2S,3R)-3-hydroxy-4-[methyl(methylcarbamoyl)amino]-1-phenylbutan-2-yl]carbamoyl}ethyl]carbamate

SMILES CNC(=O)N(C)C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)OCc1ccccc1

InChI Key InChIKey=ZMVQTFDECGHPLO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 473   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Monsanto Corporate Research

LigandPNGBDBM473(benzyl N-[(1S)-2-carbamoyl-1-{[(2S,3R)-3-hydroxy-4...)
Affinity DataIC50: 1.00E+4nMpH: 6.4 T: 2°CAssay Description:IC50 values for inhibition of recombinant HIV protease were determined using the spectrofluorometric assay, which utilized an intramolecularly quench...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2004
Entry Details Article
PubMed