BDBM473017 (R)-3-(cyclopentylmethyl)-4-ethyl-6,6a,7,8,9,10- hexahydro-5H-pyrazino[1,2-a][1,8]naphthyridine::US10836764, Compound 171

SMILES CCc1c(CC2CCCC2)cnc2N3CCNC[C@H]3CCc12

InChI Key InChIKey=CMOXGSMXWFCHLU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 473017   

Target5-hydroxytryptamine receptor 2B(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM473017((R)-3-(cyclopentylmethyl)-4-ethyl-6,6a,7,8,9,10- h...)
Affinity DataKi:  6.35nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM473017((R)-3-(cyclopentylmethyl)-4-ethyl-6,6a,7,8,9,10- h...)
Affinity DataKi:  52nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM473017((R)-3-(cyclopentylmethyl)-4-ethyl-6,6a,7,8,9,10- h...)
Affinity DataKi:  351nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent