BDBM473604 US10844062, Example 40

SMILES [O-][N+](=O)c1cc(cc(c1)C(F)(F)F)C(=O)Nc1ccc(F)c(Nc2ncccc2-c2ncnc3[nH]cnc23)c1F

InChI Key InChIKey=ORGTVRPFWVNIRX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 473604   

TargetVascular endothelial growth factor receptor 2(Human)
Incheon University Industry Academic Cooperation Foundation

US Patent
LigandPNGBDBM473604(US10844062, Example 40)
Affinity DataIC50: 96nMAssay Description:The inhibitory activities of the compounds of the present invention against VEGFR-2 tyrosine kinase were analyzed using ADP-Glo kinase assay kit comm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent