BDBM473736 3-(3-Chloro-1H-pyrrolo[2,3-b]pyridin-2-yl)- 1-cyclopentyl-1H-pyrazolo[3,4-d]pyrimidin- 4-amine::US10844067, Example 79::US11661423, Example 79
SMILES Nc1ncnc2n(nc(-c3[nH]c4ncccc4c3Cl)c12)C1CCCC1
InChI Key InChIKey=CAZLNMQWQAFXNI-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 473736
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Cancer Research Technology
US Patent
Cancer Research Technology
US Patent
Affinity DataIC50: 1.60nMAssay Description:RET and KDR: Kinase activity was detected using CisBio HTRF kinEASE kit based on time-resolved fluorescence transfer (FRET). The assay was performed ...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cancer Research Technology
US Patent
Cancer Research Technology
US Patent
Affinity DataIC50: 1.29E+3nMAssay Description:RET and KDR: Kinase activity was detected using CisBio HTRF kinEASE kit based on time-resolved fluorescence transfer (FRET). The assay was performed ...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret [V804M](Homo sapiens (Human))
Cancer Research Technology
US Patent
Cancer Research Technology
US Patent
Affinity DataIC50: 28.5nMAssay Description:Kinase activity was detected using CisBio HTRF kinEASE kit based on time-resolved fluorescence transfer (FRET). The assay was performed in 384-well w...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Cancer Research Technology
US Patent
Cancer Research Technology
US Patent
Affinity DataIC50: 1.60nMAssay Description:Kinase activity was detected using CisBio HTRF kinEASE kit based on time-resolved fluorescence transfer (FRET). The assay was performed in 384-well w...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cancer Research Technology
US Patent
Cancer Research Technology
US Patent
Affinity DataIC50: 1.29E+3nMAssay Description:Kinase activity was detected using CisBio HTRF kinEASE kit based on time-resolved fluorescence transfer (FRET). The assay was performed in 384-well w...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret [V804M](Homo sapiens (Human))
Cancer Research Technology
US Patent
Cancer Research Technology
US Patent
Affinity DataIC50: 28.5nMAssay Description:RET and KDR: Kinase activity was detected using CisBio HTRF kinEASE kit based on time-resolved fluorescence transfer (FRET). The assay was performed ...More data for this Ligand-Target Pair