BDBM474013 N-{4-Methyl-5-[1-oxo-2-(propan-2-yl)-7-sulfamoyl-2,3-dihydro-1H- isoindol-5-yl]-1,3-thiazol-2-yl}acetamide::US10858355, Example 21

SMILES CC(C)N1Cc2cc(cc(c2C1=O)S(N)(=O)=O)-c1sc(NC(C)=O)nc1C

InChI Key InChIKey=UZTFTLUAQBPIDN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 474013   

LigandPNGBDBM474013(N-{4-Methyl-5-[1-oxo-2-(propan-2-yl)-7-sulfamoyl-2...)
Affinity DataIC50: 1.26nMAssay Description:The activity of recombinant human PI3Kγ (aa144-1102)-6His was determined by measuring the ADP level after phosphorylation of DiC8-PIP2 using a c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent