BDBM474032 US10858356, Example 12

SMILES COc1nccc(-c2ccc3n(c(cc3c2)C(=O)N2CCc3nn(c(c3[C@@H]2C)-n2ccn(-c3ccc4n(C)ncc4c3)c2=O)-c2cc(C)c(F)c(C)c2)[C@]2(C[C@@H]2C)c2noc(=O)[nH]2)c1C

InChI Key InChIKey=FQIMJIGBVXTYQT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 474032   

TargetGlucagon-like peptide 1 receptor(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM474032(US10858356, Example 12)
Affinity DataEC50:  2.70nMAssay Description:hGLP1R-HEK293 was seeded in 96 well plates at 2.0×104 cells per well and cultured over night. The medium for culturing the cells was changed to 50 &#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent