BDBM474044 US10858356, Example 24

SMILES C[C@H]1C[C@]1(c1noc(=O)[nH]1)n1c(cc2cc(ccc12)C1CCOCC1)C(=O)N1CCc2nn(c(c2[C@@H]1C)-n1ccn(-c2ccc3c(CCOC3(C)C)c2)c1=O)-c1cc(C)c(F)c(C)c1

InChI Key InChIKey=MZZVULXCEZFAPC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 474044   

TargetGlucagon-like peptide 1 receptor(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM474044(US10858356, Example 24)
Affinity DataEC50:  2.5nMAssay Description:hGLP1R-HEK293 was seeded in 96 well plates at 2.0×104 cells per well and cultured over night. The medium for culturing the cells was changed to 50 &#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent