BDBM474096 US10858356, Example 76

SMILES COCCn1ncc2cc(ccc12)-n1ccn(-c2c3CN(CCc3nn2-c2cc(C)c(F)c(C)c2)C(=O)c2cc3cc(ccc3n2[C@]2(C[C@@H]2C)c2noc(=O)[nH]2)C2CCOC(C)(C)C2)c1=O

InChI Key InChIKey=FLGAGDVAELSABB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 474096   

TargetGlucagon-like peptide 1 receptor(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM474096(US10858356, Example 76)
Affinity DataEC50:  2.40nMAssay Description:hGLP1R-HEK293 was seeded in 96 well plates at 2.0×104 cells per well and cultured over night. The medium for culturing the cells was changed to 50 &#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent