BDBM474099 3-[(1S,2S)-1-[2-[2-(4-fluoro-3,5-dimethylphenyl)-3-[3-(1-methylindazol-5-yl)-2-oxoimidazol-1-yl]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carbonyl]-5-(oxan-4-yl)indol-1-yl]-2-(hydroxymethyl)cyclopropyl]-4H-1,2,4-oxadiazol-5-one::US10858356, Example 79

SMILES Cc1cc(cc(C)c1F)-n1nc2CCN(Cc2c1-n1ccn(-c2ccc3n(C)ncc3c2)c1=O)C(=O)c1cc2cc(ccc2n1[C@]1(C[C@@H]1CO)c1noc(=O)[nH]1)C1CCOCC1

InChI Key InChIKey=GLUHYLPHDBNOLT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 474099   

TargetGlucagon-like peptide 1 receptor(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM474099(3-[(1S,2S)-1-[2-[2-(4-fluoro-3,5-dimethylphenyl)-3...)
Affinity DataEC50:  2.40nMAssay Description:hGLP1R-HEK293 was seeded in 96 well plates at 2.0×104 cells per well and cultured over night. The medium for culturing the cells was changed to 50 &#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent