BDBM47424 4-[[[(Z)-2-hydroxy-1,2-diphenyl-vinyl]hydrazono]methyl]-o-benzoquinone::4-[[[(Z)-2-hydroxy-1,2-diphenylethenyl]hydrazinylidene]methyl]cyclohexa-3,5-diene-1,2-dione::4-[[[(Z)-2-oxidanyl-1,2-diphenyl-ethenyl]hydrazinylidene]methyl]cyclohexa-3,5-diene-1,2-dione::MLS000394999::SMR000248455::cid_15945139

SMILES CC[C@H]1CCC[C@@]1(N)COc4cc(c2cnc3cccc(OC)n23)cc(SC)c4C#N

InChI Key InChIKey=PTPHBFWUIVDPAV-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 47424   

TargetSerine/threonine-protein kinase SIK1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 47424BDBM47424(US20240124450, Example 10B)
Affinity DataIC50: 0.300nMAssay Description:Salt Induced Kinase (SIK) activity is determined by measuring the effect of a test agent on the activity of the appropriate SIK enzyme to phosphoryla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 47424BDBM47424(US20240124450, Example 10B)
Affinity DataIC50: 0.5nMAssay Description:Salt Induced Kinase (SIK) activity is determined by measuring the effect of a test agent on the activity of the appropriate SIK enzyme to phosphoryla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK3(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 47424BDBM47424(US20240124450, Example 10B)
Affinity DataIC50: 1nMAssay Description:Salt Induced Kinase (SIK) activity is determined by measuring the effect of a test agent on the activity of the appropriate SIK enzyme to phosphoryla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent