BDBM474345 6-benzhydryl-11-hydroxy-5,6-dihydro-10H- imidazo[1,2-d]pyrido[2,1-f][1,2,4]triazin-10- one::US10858366, Example 6::US11453677, Example 6

SMILES Oc1c2-c3nccn3CN(C(c3ccccc3)c3ccccc3)n2ccc1=O

InChI Key InChIKey=YNCXGUBKNGPNDS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474345   

TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474345(6-benzhydryl-11-hydroxy-5,6-dihydro-10H- imidazo[1...)
Affinity DataIC50:  40nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474345(6-benzhydryl-11-hydroxy-5,6-dihydro-10H- imidazo[1...)
Affinity DataIC50:  40nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent