BDBM474393 US10858368, Entry 13::US11319327, Entry 13

SMILES Cc1ccc(cc1)N1CCN(CCC2CC3(CCN(CC3)S(=O)(=O)C3CCOCC3)C(=O)O2)CC1

InChI Key InChIKey=RJOLIGKCRQYQOL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 474393   

Target5-hydroxytryptamine receptor 7(Human)
Temple University

US Patent
LigandPNGBDBM474393(US10858368, Entry 13 | US11319327, Entry 13 | US20...)
Affinity DataIC50: 96nMAssay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 7(Human)
Temple University

US Patent
LigandPNGBDBM474393(US10858368, Entry 13 | US11319327, Entry 13 | US20...)
Affinity DataIC50: 96nMAssay Description:A stock concentration of 5 nM [3H]LSD (lysergic acid diethyl amide) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Ali...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

Target5-hydroxytryptamine receptor 7(Human)
Temple University

US Patent
LigandPNGBDBM474393(US10858368, Entry 13 | US11319327, Entry 13 | US20...)
Affinity DataIC50: 96nMAssay Description:A VEGFR2 tagged T7 phage strain was prepared in an Escherichia coli (E. coli) derived from the BL21 strain. The E. coli were grown to log-phase, infe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent