BDBM47446 2-chloranyl-N-[[3-(4-chlorophenyl)-1,2-oxazol-5-yl]methyl]ethanamide::2-chloro-N-[[3-(4-chlorophenyl)-1,2-oxazol-5-yl]methyl]acetamide::2-chloro-N-[[3-(4-chlorophenyl)-5-isoxazolyl]methyl]acetamide::2-chloro-N-[[3-(4-chlorophenyl)isoxazol-5-yl]methyl]acetamide::2-chloro-N-{[3-(4-chlorophenyl)-5-isoxazolyl]methyl}acetamide::MLS000764176::SMR000335010::cid_1477188

SMILES CSc4cc(c1cnc2ccccn12)cc(OC[C@]3(N)CCSC3)c4C#N

InChI Key InChIKey=UQMGWSHJWYKFGS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 47446   

TargetSerine/threonine-protein kinase SIK2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 47446BDBM47446(US20240124450, Example 23B)
Affinity DataIC50: 0.800nMAssay Description:Salt Induced Kinase (SIK) activity is determined by measuring the effect of a test agent on the activity of the appropriate SIK enzyme to phosphoryla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 47446BDBM47446(US20240124450, Example 23B)
Affinity DataIC50: 1.10nMAssay Description:Salt Induced Kinase (SIK) activity is determined by measuring the effect of a test agent on the activity of the appropriate SIK enzyme to phosphoryla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK3(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 47446BDBM47446(US20240124450, Example 23B)
Affinity DataIC50: 3.10nMAssay Description:Salt Induced Kinase (SIK) activity is determined by measuring the effect of a test agent on the activity of the appropriate SIK enzyme to phosphoryla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent