BDBM47457 Butyric acid N',N'-dimethyl-N-(2,2,3,3-tetracyano-4-methyl-cyclopentyl)-hydrazide::MLS001049390::N',N'-dimethyl-N-(2,2,3,3-tetracyano-4-methyl-cyclopentyl)butanehydrazide::N',N'-dimethyl-N-(2,2,3,3-tetracyano-4-methyl-cyclopentyl)butyrohydrazide::N',N'-dimethyl-N-(2,2,3,3-tetracyano-4-methylcyclopentyl)butanehydrazide::SMR000426787::cid_3270222

SMILES COc5cc(c1cnc2cccc(OC)n12)cc(OC[C@@]3(N)CCC[C@H]3CC4CC4)c5C#N

InChI Key InChIKey=QCESUACIVCNKOD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 47457   

TargetSerine/threonine-protein kinase SIK1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 47457BDBM47457(US20240124450, Example 32C)
Affinity DataIC50: 0.5nMAssay Description:Salt Induced Kinase (SIK) activity is determined by measuring the effect of a test agent on the activity of the appropriate SIK enzyme to phosphoryla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 47457BDBM47457(US20240124450, Example 32C)
Affinity DataIC50: 0.800nMAssay Description:Salt Induced Kinase (SIK) activity is determined by measuring the effect of a test agent on the activity of the appropriate SIK enzyme to phosphoryla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK3(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 47457BDBM47457(US20240124450, Example 32C)
Affinity DataIC50: 2nMAssay Description:Salt Induced Kinase (SIK) activity is determined by measuring the effect of a test agent on the activity of the appropriate SIK enzyme to phosphoryla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent