BDBM475489 1-[5-Chloro-6-(propane-2-sulfonyl)-1H-benzoimidazol-2-::US10851083, Example 101::US11618744, Example 101

SMILES CC(C)S(=O)(=O)c1cc2[nH]c(nc2cc1Cl)-n1cc(cn1)C(O)=O

InChI Key InChIKey=OLBQXWOEVGSIIM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475489   

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475489(1-[5-Chloro-6-(propane-2-sulfonyl)-1H-benzoimidazo...)
Affinity DataIC50: 50.1nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475489(1-[5-Chloro-6-(propane-2-sulfonyl)-1H-benzoimidazo...)
Affinity DataIC50: 50.1nMAssay Description:The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
US Patent