BDBM475496 1-(6-Methanesulfinyl-5-trifluoromethyl-1H-::US10851083, Example 108::US11618744, Example 108

SMILES CS(=O)c1cc2[nH]c(nc2cc1C(F)(F)F)-n1cc(cn1)C(O)=O

InChI Key InChIKey=OSKPMKMIUNDZBD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475496   

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475496(1-(6-Methanesulfinyl-5-trifluoromethyl-1H- | US108...)
Affinity DataIC50: 50.1nMAssay Description:The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475496(1-(6-Methanesulfinyl-5-trifluoromethyl-1H- | US108...)
Affinity DataIC50: 50.1nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent