BDBM475938 US10865195, Compound 4

SMILES C[C@@H]1CN(Cc2ccc(OCCF)cn2)CCN1C(=O)CCc1ccc(cc1Cn1nnc(C)n1)C(F)(F)F

InChI Key InChIKey=KYWZZLHFJPTLOH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 475938   

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM475938(US10865195, Compound 4)
Affinity DataIC50: 2nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent