BDBM475939 Preparation of (1R,2S,6R,11R)-1-(2,5,8,11,14-pentaoxahexadecan-16-yloxy)-3-(cyclopropylmethyl)-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methanobenzo[d]azocin-8-ol ::US10865186, Compound 25

SMILES COCCOCCOCCOCCO[C@@H]1c2ccc(O)cc2[C@]2(C)CCN(CC3CC3)[C@H]1[C@@H]2C

InChI Key InChIKey=YKSGYQXFOQMCSP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475939   

TargetKappa-type opioid receptor(Human)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 475939BDBM475939(Preparation of (1R,2S,6R,11R)-1-(2,5,8,11,14-penta...)
Affinity DataKi:  955nMAssay Description:The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 475939BDBM475939(Preparation of (1R,2S,6R,11R)-1-(2,5,8,11,14-penta...)
Affinity DataKi:  3.92E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent