BDBM475952 US10865206, Compound 114

SMILES CC(C)(C)OC(=O)Nc1ccc(cc1)C(=O)N[C@H]1CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12

InChI Key InChIKey=ITXHFVWCIVQFLX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 475952   

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM475952(US10865206, Compound 114)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies(Grand Island, N.Y.) using their commercially available Adapta kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent