BDBM476205 US10865384, Compound IM-18::US10865384, Example 4b

SMILES Cc1cccc(c1)-c1nc([nH]c1C1=CCOCC1)-c1c(F)cccc1F

InChI Key InChIKey=DQHWPNGYYKSNRQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 476205   

TargetMitogen-activated protein kinase 14(Human)
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476205(US10865384, Example 4b | US10865384, Compound IM-1...)
Affinity DataIC50: 14nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter p38 MAP kinase binding assay from D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetCasein kinase I isoform epsilon(Human)
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476205(US10865384, Example 4b | US10865384, Compound IM-1...)
Affinity DataIC50: 1.24E+3nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter p38 MAP kinase binding assay from D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent