BDBM476436 1-chloronaphthalen-2-yl (3S)-4-{N2- [4-(aminomethyl)cyclohexyl]-N6,N6- dimethyl-D-lysyl}-3-{[4- (aminomethyl)-3- methoxybenzyl]carbamoyl}piperazine- 1-carboxylate::US10875851, Example 92

SMILES COc1cc(CNC(=O)[C@@H]2CN(CCN2C(=O)[C@@H](CCCCN(C)C)NC2CCC(CN)CC2)C(=O)Oc2ccc3ccccc3c2Cl)ccc1CN

InChI Key InChIKey=AGTKCJQDBPLCPC-GIZZIATHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476436   

TargetCoagulation factor XII(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476436(1-chloronaphthalen-2-yl (3S)-4-{N2- [4-(aminomethy...)
Affinity DataIC50:  2.90nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIIa can be determined using a relevant purified serin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent