BDBM476664 US10870625, Compound 54

SMILES CCc1nc(N)nc(N)c1C#CC(C)c1cc2OCOc2c(c1)-c1cncn1C

InChI Key InChIKey=PRCKWFFFSQYNSS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476664   

TargetDihydrofolate reductase(Human)
University of Connecticut

US Patent
LigandPNGBDBM476664(US10870625, Compound 54)
Affinity DataIC50: 323nMAssay Description:Enzyme activity and inhibition assays were performed by monitoring the NADPH-dependent reduction of dihydrofolate catalyzed by the DHFR enzyme. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent