BDBM477533 US10889555, Example 305::US10889555, Example 306::US11634395, Example 306

SMILES COc1cc(Cl)ccc1S(=O)(=O)N[C@@H]([C@H](C)c1c(F)ccc(-c2cnn(C)c2)c1C)c1n[nH]c(=O)o1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 477533   

TargetMuscarinic acetylcholine receptor M1/M2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM477533(US10889555, Example 305 | US10889555, Example 306 ...)
Affinity DataIC50:  240nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Taiho Pharmaceutial

US Patent
LigandPNGBDBM477533(US10889555, Example 305 | US10889555, Example 306 ...)
Affinity DataIC50:  90nMAssay Description:The inhibitory activity against the ribonucleotide reduction reaction (hereinafter referred to as RNR reaction) of the test compound was determined b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1/M2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM477533(US10889555, Example 305 | US10889555, Example 306 ...)
Affinity DataIC50:  90nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent