BDBM477580 Methyl 6-({[1-(3,5-difluorophenyl)-4,5,6,7-tetrahydro-1H-indazol-4-yl]amino}carbonyl)nicotinate::US10889564, Example 9

SMILES COC(=O)c1ccc(nc1)C(=O)NC1CCCc2c1cnn2-c1cc(F)cc(F)c1

InChI Key InChIKey=VXEDOXDHXQMWHR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 477580   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Genase Therapeutics

US Patent
LigandPNGBDBM477580(US10889564, Example 9 | Methyl 6-({[1-(3,5-difluor...)
Affinity DataIC50: 1.00E+4nMAssay Description:Assay A: DHODH enzyme assays were performed with 6 nM recombinant human DHODH (purified essentially as described by Walse et. al., Biochemistry, 47, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent