BDBM477941 2-oxo-4-(6-azaspiro[2.5]octane-6-yl)-1,2-dihydro-1,7-naphthyridin-3-carbonitrile ::US10889591, Compound 25::US11434248, Compound 25

SMILES O=c1[nH]c2cnccc2c(N2CCC3(CC3)CC2)c1C#N

InChI Key InChIKey=LGZFQNJXGXCQLM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 477941   

LigandPNGBDBM477941(US10889591, Compound 25 | 2-oxo-4-(6-azaspiro[2.5]...)
Affinity DataIC50: 3nMAssay Description:Inhibition of PDE9A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM477941(US10889591, Compound 25 | 2-oxo-4-(6-azaspiro[2.5]...)
Affinity DataIC50: 29nMAssay Description:1. Experimental materials and instrumentsPDE9A2 Enzyme (BPS, Cat. No. 60090)384-well plate (Perkin Elmer, Cat. No. 6007279)2. Experimental procedureP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

LigandPNGBDBM477941(US10889591, Compound 25 | 2-oxo-4-(6-azaspiro[2.5]...)
Affinity DataIC50: 29nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2022
Entry Details
US Patent