BDBM477968 6-(aminomethyl)-2-oxo-4-(7-azaspiro[3.5]nonane-7-yl)-1,2-dihydro-1,7-naphthyridin-3-carbonitrile trifluoroacetate ::US10889591, Compound 78

SMILES N#Cc1c(N2CCC3(CCC3)CC2)c2cc(CN)ncc2[nH]c1=O

InChI Key InChIKey=TVSVLGNIJDHUDM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 477968   

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Nanjing Transthera Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 477968BDBM477968(US10889591, Compound 78 | 6-(aminomethyl)-2-oxo-4-...)
Affinity DataIC50: 33nMAssay Description:1. Experimental materials and instrumentsPDE9A2 Enzyme (BPS, Cat. No. 60090)384-well plate (Perkin Elmer, Cat. No. 6007279)2. Experimental procedureP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent