BDBM479491 3-amino-N-((6-(dimethylamino)pyridin- 2-yl)methyl)-6-(1-methyl-6-oxo-1,6- dihydropyridin-3-yl)-5-(oxazol-2-yl) pyrazine-2-carboxamide::US10898481, Compound 16::US11571420, Compound 16

SMILES CN(C)c1cccnc1CNC(=O)c1nc(-c2ccc(=O)n(C)c2)c(nc1N)-c1ncco1

InChI Key InChIKey=GYSSUJQTLZXOER-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 479491   

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM479491(3-amino-N-((6-(dimethylamino)pyridin- 2-yl)methyl)...)
Affinity DataIC50: 3.90nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM479491(3-amino-N-((6-(dimethylamino)pyridin- 2-yl)methyl)...)
Affinity DataIC50: 3.90nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
TBA

US Patent
LigandPNGBDBM479491(3-amino-N-((6-(dimethylamino)pyridin- 2-yl)methyl)...)
Affinity DataIC50: 15nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
TBA

US Patent
LigandPNGBDBM479491(3-amino-N-((6-(dimethylamino)pyridin- 2-yl)methyl)...)
Affinity DataIC50: 15nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent