BDBM479512 3-amino-N-(2,6-difluorobenzyl)-6-(1- methyl-6-oxo-1,6-dihydropyridazin-3- yl)-5-(oxazol-2-yl)pyrazine-2- carboxamide::US10898481, Compound 37::US11571420, Compound 37

SMILES Cn1nc(ccc1=O)-c1nc(C(=O)NCc2c(F)cccc2F)c(N)nc1-c1ncco1

InChI Key InChIKey=SUGJXKNNUQNAKI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 479512   

TargetAdenosine receptor A2a(Human)
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM479512(3-amino-N-(2,6-difluorobenzyl)-6-(1- methyl-6-oxo-...)
Affinity DataIC50: 1nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM479512(3-amino-N-(2,6-difluorobenzyl)-6-(1- methyl-6-oxo-...)
Affinity DataIC50: 1nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent