BDBM479516 3-amino-6-(1H-benzo[d]imidazol-5-yl)- N-((3-fluoropyridin-2-yl)methyl)-5- (oxazol-2-yl)pyrazine-2-carboxamide::US10898481, Compound 47::US11571420, Compound 47

SMILES Nc1nc(-c2ncco2)c(nc1C(=O)NCc1ncccc1F)-c1ccc2[nH]cnc2c1

InChI Key InChIKey=GYCBAWUOCFEMQV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 479516   

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM479516(3-amino-6-(1H-benzo[d]imidazol-5-yl)- N-((3-fluoro...)
Affinity DataIC50: 2.60nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM479516(3-amino-6-(1H-benzo[d]imidazol-5-yl)- N-((3-fluoro...)
Affinity DataIC50: 2.60nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
TBA

US Patent
LigandPNGBDBM479516(3-amino-6-(1H-benzo[d]imidazol-5-yl)- N-((3-fluoro...)
Affinity DataIC50: 696nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
TBA

US Patent
LigandPNGBDBM479516(3-amino-6-(1H-benzo[d]imidazol-5-yl)- N-((3-fluoro...)
Affinity DataIC50: 696nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent