BDBM479517 3-amino-N-((6-aminopyridin-2-yl) methyl)-6-(imidazo[1,2-a]pyridin- 6-yl)-5-(oxazol-2-yl)pyrazine-2- carboxamide::US10898481, Compound 48::US11571420, Compound 48

SMILES Nc1cccc(CNC(=O)c2nc(-c3ccc4nccn4c3)c(nc2N)-c2ncco2)n1

InChI Key InChIKey=WJBZHWNSLMGASE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 479517   

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM479517(3-amino-N-((6-aminopyridin-2-yl) methyl)-6-(imidaz...)
Affinity DataIC50: 3.10nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM479517(3-amino-N-((6-aminopyridin-2-yl) methyl)-6-(imidaz...)
Affinity DataIC50: 3.10nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
TBA

US Patent
LigandPNGBDBM479517(3-amino-N-((6-aminopyridin-2-yl) methyl)-6-(imidaz...)
Affinity DataIC50: 67nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
TBA

US Patent
LigandPNGBDBM479517(3-amino-N-((6-aminopyridin-2-yl) methyl)-6-(imidaz...)
Affinity DataIC50: 67nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent