BDBM479535 (R)-3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl)-5-(oxazol-2-yl)-N- ((tetrahydrofuran-3-yl)methyl)pyrazine- 2-carboxamide::US10898481, Compound 136::US11571420, Compound 136

SMILES Cc1cnc2ccc(cn12)-c1nc(C(=O)NC[C@H]2CCOC2)c(N)nc1-c1ncco1

InChI Key InChIKey=QFRUAJNAMIIGGK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 479535   

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM479535((R)-3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl...)
Affinity DataIC50: 1.70nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM479535((R)-3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl...)
Affinity DataIC50: 1.70nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM479535((R)-3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl...)
Affinity DataIC50: 182nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM479535((R)-3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl...)
Affinity DataIC50: 182nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent