BDBM480396 (R)-3-(tert-butyl)-N-(1-(3-fluoro-2-methyl-4-(4-((1-methyl-1H-pyrazol-4-yl)amino)-1,3,5-triazin-2-yl)phenyl)ethyl)isoxazole-5-carboxamide ::US10899753, Example 75

SMILES C[C@@H](NC(=O)c1cc(no1)C(C)(C)C)c1ccc(c(F)c1C)-c1ncnc(Nc2cnn(C)c2)n1

InChI Key InChIKey=LXWMDULLKDKERI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480396   

TargetTyrosine-protein kinase BTK(Human)
Biogen Ma

US Patent
LigandPNGBDBM480396((R)-3-(tert-butyl)-N-(1-(3-fluoro-2-methyl-4-(4-((...)
Affinity DataIC50: 1nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
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Date in BDB:
8/15/2021
Entry Details
US Patent